Windows’ driver signature enforcement often blocks the required usb2ser (MediaTek Preloader VCOM) drivers. Users frequently have to disable signature enforcement or use a Windows 7 VM. Version 6.2216 doesn't solve this.
Usually a driver issue or an incorrect DA file. Reinstall VCOM drivers. sp flash tool 6.2216
If you have an unsupported device, you can extract the DA_SWSEC.bin from an official firmware package and rename it to MTK_AllInOne_DA.bin to improve compatibility. sp flash tool 6.2216